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December 25, 2015ObesityOpen Access

A weight reduction program in children with obesity significantly increased general heart rate variability (P<0.001) and parasympathetic regulation (P<0.01), but did not alter stress reactivity.

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Why the study?

Does an inpatient weight reduction program improve baseline and stress-induced heart rate variability in children with obesity?

Population

87 children, comprising 60 children with obesity and 27 age- and sex-matched normal-weight healthy…

Comparison

Inpatient weight reduction program vs Normal-weight healthy peers and pre-treatment…

Design

Cohort

Key result

A weight reduction program in children with obesity significantly increased general heart rate variability (P<0.001) and parasympathetic regulation (P<0.01), but did not alter stress reactivity.

Authors

NMNazar MazurakHSHelene SauerKWKatja Weimer

Discussion

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Overview

May support inpatient autonomic benefits in obese children; leaves open effects on stress reactivity and outcomes.

Study Design

Type

Observational (n=87)

Structured PICO

Does an inpatient weight reduction program improve baseline and stress-induced heart rate variability in children with obesity?

P
Population
87 children, comprising 60 with obesity and 27 age- and sex-matched normal-weight controls, evaluated for heart rate variability before and after a weight reduction program.
E
Exposure
Inpatient weight reduction program
C
Comparator
Normal-weight healthy peers (for baseline comparison) and pre-treatment baseline (for the weight reduction intervention)
O
Outcome
Heart rate variability (HRV) at baseline, during a mental stress test, and a subsequent recovery periodsurrogate

Main Result

p-value: p=<0.001

An inpatient weight reduction program in children with obesity shifts baseline autonomic activity toward parasympathetic dominance but does not alter autonomic reactivity during stress conditions.

Cite This Study

Mazurak et al. (2015) conducted an observational in Obesity (n=87). Weight reduction program vs. Baseline values and normal-weight peers was evaluated on Heart rate variability (HRV) at baseline, during mental stress, and recovery (p=<0.001). A weight reduction program in children with obesity significantly increased general heart rate variability (P<0.001) and parasympathetic regulation (P<0.01), but did not alter stress reactivity.

synapsesocial.com/papers/6a5e0a8044d40cfb0237b678https://doi.org/10.1002/oby.21355
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