Key result
Adenosine use for out-of-hospital supraventricular tachycardia resulted in a similar rate of conversion to sinus rhythm compared to a historical period of verapamil use (69% vs 88%; P=0.11).
Why the study?
Does adenosine compared to verapamil improve conversion rates to sinus rhythm in out-of-hospital patients with SVT?
Population
211 patients with out-of-hospital supraventricular tachycardia treated in a metropolitan…
Comparison
Adenosine administered by paramedics for… vs Verapamil administered by paramedics for…
Design
Cohort
Follow-up
Until emergency department disposition
Authors
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Adenosine may be comparable for out-of-hospital SVT; leaves open need for randomized trials versus verapamil.
Cohort (n=211)
Does adenosine compared to verapamil improve conversion rates to sinus rhythm in out-of-hospital patients with SVT?
Absolute Event Rate: 69% vs 88%
p-value: p=0.11
Adenosine and verapamil are equally successful in converting out-of-hospital SVT, though rhythm misidentification remains a critical issue leading to severe adverse events when verapamil is mistakenly given for wide-complex tachycardia.
Brady et al. (1996) conducted a cohort in Out-of-hospital supraventricular tachycardia (SVT) (n=211). Adenosine vs. Verapamil was evaluated on Conversion to sinus rhythm (p=0.11). Adenosine use for out-of-hospital supraventricular tachycardia resulted in a similar rate of conversion to sinus rhythm compared to a historical period of verapamil use (69% vs 88%; P=0.11).
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