Key result
Visceral adipose tissue was positively associated with total cholesterol (ß=0.39, p<0.001) and LDL (ß=0.37, p<0.001), and inversely associated with HDL (ß=-0.14, p<0.001) independent of BMI.
Why the study?
Obesity increases cardiovascular disease risk, but whether adipose tissue relates to dyslipidemia and subsequent cardiovascular events remains unknown.
Are adipose tissue depots associated with dyslipidemia in subjects without cardiovascular disease?
Population
384 participants without CVD from the KORA-MRI study
Comparison
Visceral, subcutaneous, and total adipose tissue levels
Design
Population-based cross-sectional study
Authors
Loading...
VAT/SAT associate with dyslipidemia independent of BMI; leaves open causal links to events and need for prospective trials.
Cross-Sectional (n=384)
Are adipose tissue depots associated with dyslipidemia in subjects without cardiovascular disease?
Effect estimate: ß = 0.39
p-value: p=<0.001
Adipose tissue depots, particularly visceral fat, are significantly associated with pro-atherogenic lipid profiles independent of BMI, highlighting their role in cardiovascular risk.
Krüchten et al. (2022) conducted a cross-sectional in Subjects without cardiovascular disease (n=384). Adipose tissue depots (visceral and subcutaneous) was evaluated on Circulating lipoproteins (total cholesterol, HDL, LDL) and triglycerides (ß = 0.39, p=<0.001). Visceral adipose tissue was positively associated with total cholesterol (ß=0.39, p<0.001) and LDL (ß=0.37, p<0.001), and inversely associated with HDL (ß=-0.14, p<0.001) independent of BMI.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: