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December 13, 2021European Journal of RadiologyOpen Access

Prognostic value of 2-[18F]FDG PET-CT in metastatic melanoma patients receiving immunotherapy

Gregor Schweighofer-Zwink Reyhaneh Manafi‐Farid Peter Kölblinger Lukas Hehenwarter Sara Harsini Christian Pirich Mohsen Beheshti

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Key Points

This research assesses how well FDG PET-CT can predict outcomes in melanoma patients undergoing immunotherapy.
Used FDG PET-CT studies at 3 and 6 months after therapy.
Extracted multiple metabolic parameters and tumor-to-background ratios (TBRs).
Correlated these metrics with overall survival (OS).
A tumor-to-background ratio (TBR) cutoff of 2.15 correlated with 3-year survival and had a sensitivity of 88.5% and specificity of 68.0%.
Suggests that FDG PET-CT metrics can effectively aid in predicting patient outcomes.

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Implication

Evaluates the prognostic value of FDG PET-CT in metastatic melanoma patients, suggesting its importance for monitoring therapy response.

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Cite This Study

Schweighofer-Zwink et al. (2021) studied this question.

synapsesocial.com/papers/6a5e19aa488486c5eff68cbf https://doi.org/10.1016/j.ejrad.2021.110107

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Keep reading

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