Key result
Surgery and systemic chemotherapy successfully treat a rare 15-cm intra-abdominal Ewing sarcoma.
Why the study?
Extraosseous Ewing sarcoma is a rare manifestation within the Ewing sarcoma tumor family with non-specific clinical manifestations, making it prone to misdiagnosis as intestinal mesenchymal tumor.
Case Report (n=1)
Giant abdominal Ewing sarcoma is a rare condition that can present with intestinal obstruction and be successfully managed with surgical resection and chemotherapy.
May guide rare giant intra-abdominal Ewing sarcoma management; extends sparse case evidence but leaves optimal protocols open.
RATIONALE: Extraosseous Ewing sarcoma (EES) is a rare manifestation within the Ewing sarcoma tumor family (ESFT). Its clinical manifestations lack specificity, intestinal obstruction is the main symptom but can also present with abdominal pain, gastrointestinal bleeding, and other discomforts, making it prone to misdiagnosis as intestinal mesenchymal tumor. PATIENT CONCERNS: A 29-year-old male was admitted to the hospital with intestinal obstruction symptoms and abdominal CT suggesting "left abdominal occupation." DIAGNOSIS: The patient was initially misdiagnosed as intestinal mesenchymal tumor, and was later definitively diagnosed as abdominal Ewing sarcoma by postoperative pathology and genetic testing. INTERVENTIONS: Due to the patient's surgical indication, surgical resection with exploratory laparotomy was performed and then the patient underwent systemic chemotherapy. OUTCOMES: Intraoperatively, we found a 15-cm tumor originating from the proximal jejunum, with invasion into the peritoneum, duodenum, jejunum, and colon. Finally, the pathological report revealed Ewing sarcoma. LESSONS: Giant abdominal Ewing sarcoma with a diameter of 15 cm is rare. Considering postoperative pathology and genetic testing, abdominal Ewing sarcoma was suspected. The patient was successfully treated using surgery.
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Yang et al. (2024) conducted a case report in Intra-abdominal Ewing sarcoma (n=1). Surgical resection with exploratory laparotomy and systemic chemotherapy was evaluated on Successful treatment and tumor resection. Surgical resection and systemic chemotherapy successfully treated a 29-year-old male with a rare 15-cm giant intra-abdominal Ewing sarcoma originating from the proximal jejunum.
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