Key result
Chemotherapy provides palliation for advanced soft tissue sarcomas and improves survival in Ewing's sarcoma, but its adjuvant value remains unproven for the majority of histological subtypes.
Why the study?
Does chemotherapy improve outcomes in patients with soft tissue sarcomas?
Population
Patients with soft tissue sarcomas
Design
Review
Authors
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Supports chemotherapy for advanced sarcomas and Ewing's; leaves open prospective validation of subtype-specific regimens.
Does chemotherapy improve outcomes in patients with soft tissue sarcomas?
Chemotherapy plays a crucial role in palliating advanced soft tissue sarcomas and is essential for specific subtypes like Ewing's sarcoma, though novel therapies are needed.
Krikelis et al. (2010) conducted a review in Soft tissue sarcomas. Chemotherapy was evaluated. Chemotherapy provides palliation for advanced soft tissue sarcomas and improves survival in Ewing's sarcoma, but its adjuvant value remains unproven for the majority of histological subtypes.
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