Answers are grounded in this paper and cite their sources.
Demonstrates regio- and enantioselective reduction of diketones, indicating broad applications for similar compounds.
On the basis of steric hindrance, one carbonyl group in a diketone can be reduced in a regioselective manner, with high enantioselectivity. The methodology can be extended to ketones with varied length of hydrocarbon chain spacing, and the products can be converted by oxidation to hydroxy esters or lactones without loss of enantiopurity.
No takes yet. Share an insight, caveat, or question.
Khamis et al. (2024) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: