Key result
The Jarvik 2000 rotary artificial heart with blood-immersed bearings demonstrated 3-year in vitro durability and 5-month in vivo calf survival with no thromboembolism.
Population
In vitro models and in vivo calf models
Design
Preclinical
Follow-up
5 months (in vivo), 3 years (in vitro)
Authors
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Preclinical durability supports bearing design iteration; leaves open human translation and long-term outcomes.
Blood-immersed bearings in rotary artificial hearts like the Jarvik 2000 show promising durability and biocompatibility in preclinical testing, allowing for system simplification and miniaturization.
Robert Jarvik (1995) studied Heart failure (preclinical/device testing). Jarvik 2000 rotary artificial heart was evaluated on In vitro durability and in vivo survival/thromboembolism. The Jarvik 2000 rotary artificial heart with blood-immersed bearings demonstrated 3-year in vitro durability and 5-month in vivo calf survival with no thromboembolism.
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