Key result
Elevated preoperative troponin T is linked to ~38% higher odds of prolonged ICU stay.
Why the study?
Prolonged postoperative ICU stays after heart valve surgery are linked to serious complications, motivating the evaluation of selected biomarkers to predict prolonged ICU stays.
Does elevated high-sensitivity troponin T predict prolonged postoperative intensive care unit stay in patients undergoing heart valve surgery?
Cohort (n=631)
No
Does elevated high-sensitivity troponin T predict prolonged postoperative intensive care unit stay in patients undergoing heart valve surgery?
Odds Ratio: 1.381 (95% CI 1.084–1.759)
p-value: p=0.014
Elevated preoperative and postoperative troponin T can identify patients at higher risk for prolonged ICU stay and worse outcomes after heart valve surgery.
May identify higher-risk valve surgery patients; extends postoperative troponin data but leaves open prospective validation.
Background: Prolonged stays in the postoperative intensive care unit (ICU) for patients undergoing heart valve surgery are mainly caused by the development of complications. In turn, with the extension of the ICU stay, there is a risk of developing further serious postoperative complications. The main aim of the present study was to evaluate selected biomarkers in terms of their predictive potential for a prolonged postoperative stay in the ICU. Methods: This prospective study was conducted on a group of patients undergoing heart valve surgery. The primary endpoint was prolonged postoperative intensive care unit stay beyond 3 days (above the median). Logistic regression analysis was used to assess the predictors of the occurrence of the primary endpoint. Results: A total of 631 patients were included in the study. The median stay in the ICU was 3 days (2–5). A total of 265 patients required a prolonged stay in the ICU. In multivariate logistic regression analysis troponin T measured before surgery (p = 0.014), EuroSCORE II operative risk score (p = 0.004), troponin T measured the day after surgery (p = 0.005), preoperative RDW level (p = 0.005) and the presence of preoperative atrial fibrillation (p = 0.002) were independent predictors of the primary endpoint. Conclusions: Patients with elevated troponin T values determined both before the procedure and in the early postoperative period should be given special attention, because this group of patients is burdened with an increased risk of prolonged stay in the postoperative ward, the occurrence of serious postoperative complications and ultimately worse prognosis.
No takes yet. Share an insight, caveat, or question.
Duchnowski et al. (2025) conducted a cohort in Valvular heart disease (n=631). Elevated high-sensitivity troponin T vs. Lower troponin T levels was evaluated on Prolonged postoperative intensive care unit stay beyond 3 days (above the median) (OR 1.381, 95% CI 1.084-1.759, p=0.014). Elevated preoperative troponin T was an independent predictor of prolonged ICU stay beyond 3 days (OR 1.381, 95% CI 1.084-1.759, p=0.014).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: