What question did this study set out to answer?

To determine whether postoperative cardiac troponin I levels or electrocardiographic changes predict extended intensive care unit and hospital stays following coronary artery bypass graft surgery.

December 22, 2004Clinical ChemistryOpen Access

Cardiac Troponin I Concentrations, but Not Electrocardiographic Results, Predict an Extended Hospital Stay after Coronary Artery Bypass Graft Surgery

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Why the study?

Does measurement of cardiac troponin I predict extended ICU and hospital stay in patients undergoing routine CABG surgery?

Population

300 patients having routine coronary artery bypass graft (CABG) surgery

Design

Cohort

Follow-up

Until hospital discharge

Authors

RSRobert F. SalamonsenSewanee: The University of the South HSHans G. SchneiderThe Alfred Hospital MBMichael BaileyBrigham Young University

Discussion

Member takes

Implication

24-h cTnI was associated with prolonged ICU and hospital stays after CABG; leaves open whether it should guide risk stratification or resource use.

Key Points

To determine whether postoperative cardiac troponin I levels or electrocardiographic changes predict extended intensive care unit and hospital stays following coronary artery bypass graft surgery.
Prospective cohort study of 300 patients undergoing routine coronary artery bypass graft surgery.
Serum cardiac troponin I concentrations measured at 6 and 24 hours postoperatively were compared with electrocardiographic results and stratified into tertiles.
Multivariate analysis evaluated predictors of prolonged intensive care unit and overall hospital stays.
Multivariate analysis demonstrated that 24-hour cardiac troponin I significantly predicted increased intensive care unit stay (P = 0.012) and prolonged hospital stay (P = 0.024).
Cardiac troponin I at 6 hours post-surgery (P = 0.29 for ICU, P = 0.9 for hospital) and electrocardiographic findings (P = 0.39 and P = 0.47, respectively) had no predictive value.
Stratification of 24-hour cardiac troponin I defined risk categories as low (<10 µg/L), equivocal (10–20 µg/L), and high (>20 µg/L).

Structured PICO

Does measurement of cardiac troponin I predict extended ICU and hospital stay in patients undergoing routine CABG surgery?

Population

300 patients having routine coronary artery bypass graft (CABG) surgery

Intervention

Measurement of cardiac troponin I (cTnI) concentrations at 6 and 24 hours after surgery and electrocardiographic (ECG) results

Outcome

Extended postoperative stay in the intensive care unit (ICU) and in the hospital

A single 24-hour postoperative cTnI measurement, but not ECG, effectively predicts extended ICU and hospital stays after routine CABG surgery, allowing for risk stratification.

Cite This Study

Salamonsen et al. (2004) studied this question.

synapsesocial.com/papers/6a8ba1dc90fae8fd47e98575 https://doi.org/10.1373/clinchem.2004.041103

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Implication

24-h cTnI was associated with prolonged ICU and hospital stays after CABG; leaves open whether it should guide risk stratification or resource use.

Cardiac Troponin I Concentrations, but Not Electrocardiographic Results, Predict an Extended Hospital Stay after Coronary Artery Bypass Graft Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Cardiac Troponin I Concentrations, but Not Electrocardiographic Results, Predict an Extended Hospital Stay after Coronary Artery Bypass Graft Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider