Key result
Baseline left ventricular dyssynchrony parameters (SPWTD ≥194 ms and TPS-SD ≥60 ms) significantly identified responders to cardiac resynchronization therapy at 6 months.
Why the study?
Does ultrasound evaluation of left ventricular myocardial deformation dyssynchrony predict response to cardiac resynchronization therapy in patients with heart failure?
Population
37 patients with dilated cardiomyopathy, New York Heart Association class III-IV, left ventricular ejection…
Design
Cohort
Follow-up
6 months
Authors
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May support dyssynchrony evaluation for CRT selection; leaves open confirmation in randomized trials.
Cohort (n=37)
Does ultrasound evaluation of left ventricular myocardial deformation dyssynchrony predict response to cardiac resynchronization therapy in patients with heart failure?
Baseline ultrasound evaluation of left ventricular myocardial deformation dyssynchrony can accurately identify heart failure patients who are likely to respond to cardiac resynchronization therapy.
Mele et al. (2006) conducted a cohort in Heart failure (n=37). Baseline left ventricular myocardial deformation dyssynchrony was evaluated on Responder to CRT at 6 months (≥20% EF increase and/or ≥15% end-systolic volume decrease). Baseline left ventricular dyssynchrony parameters (SPWTD ≥194 ms and TPS-SD ≥60 ms) significantly identified responders to cardiac resynchronization therapy at 6 months.
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