Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Acute STEMI

BACKGROUND percutaneous coronary intervention (PCI) is an excellent therapy for artery disease, the effects of PCI on left ventricular diastolic function not been systematically investigated in patients of Acute ST Elevation Infarction (STEMI) in our population. The aim of this study was to the reversibility of these diastolic abnormalities and improvement in ventricular diastolic function by using echocardiographic diastolic parameters patients with Acute STEMI in the setting of PCI and thus determine the effects improved myocardial perfusion on impaired left ventricular diastolic . total of 100 consecutive patients admitted to Intensive Coronary Care Unit (ICCU), was included in the study. Echocardiography was done before PCI and 48 after PCI, to evaluate the indices of LV diastolic function in these patients. mean age of the patients was 52.04 ± 9.49 years, and majority of patients males (84%). All had mild to moderate degree of left ventricular diastolic . Mitral E wave velocity (63.41 cm/s ± 19.93 before treatment versus 71.51 cm/s ± 9.56, 48 hours after treatment), the peak velocity of late filling due atrial contraction (mitral A wave velocity) (75.93 cm/s ± 20.3 before treatment . 78.96 cm/s ± 24.18, 48 hours after treatment), E/A ratio (1.03 ± 0.3 before vs. 0.98 ± 0.24, 48 hours after treatment) showed improvement after . After PCI deceleration time (DT) decreased (210.15 msec ± 47.43 before versus 201.64 msec ± 28.15, 48 hours after treatment), and the was statistically significant (p<0.001). It is notable that early diastolic annular velocity (E’) improved significantly 48 hours after PCI (5.81 cm/s ± 1.65 before treatment vs. 7.96 cm/s ± 1.95, 48 hours after treatment, p < 0.001). / E2 ratio showed significant change 48 hours after PCI; it was statistically (10.17 ± 2.26 before treatment vs. 8.83 ± 1.7, 48 hours after treatment <0.001). in some indices of left ventricular diastolic function after PCI that PCI can be an effective modality of treatment for diastolic caused by myocardial ischemia and revascularization can restore properties of the heart after the insult in STEMI patients and thus prevent progression to HFPEF.