Key result
A risk-scoring system using fever duration ≥9.5 days, CRP ≥88 mg/L, and NLR ≥1.69 predicted IVIG resistance in Kawasaki disease with 76.47% sensitivity and 71.05% specificity.
Why the study?
Despite routine IVIG treatment in Kawasaki disease, there remains substantial risk for IVIG resistance and coronary artery lesion development, prompting evaluation of risk factors in Turkish children.
What are the risk factors for IVIG resistance and coronary arterial lesions in Turkish children with Kawasaki disease?
Population
94 Turkish children with Kawasaki disease
Comparison
IVIG resistant vs IVIG responsive patients
Design
Retrospective cohort study
Authors
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A new risk-scoring system based on fever duration, CRP, and NLR can predict IVIG resistance in Turkish children with Kawasaki disease, potentially guiding optimal treatment to prevent coronary artery lesions.
Cohort (n=94)
What are the risk factors for IVIG resistance and coronary arterial lesions in Turkish children with Kawasaki disease?
p-value: p=< 0.05
A new risk-scoring system based on fever duration, CRP, and NLR can predict IVIG resistance in Turkish children with Kawasaki disease, potentially guiding optimal treatment to prevent coronary artery lesions.
Türkuçar et al. (2020) conducted a cohort in Kawasaki disease (n=94). IVIG resistance vs. IVIG responsive was evaluated on Coronary artery lesions (CALs) (p=< 0.05). A risk-scoring system using fever duration ≥9.5 days, CRP ≥88 mg/L, and NLR ≥1.69 predicted IVIG resistance in Kawasaki disease with 76.47% sensitivity and 71.05% specificity.
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