Key result
Antidepressant treatment reduced depressive symptoms and improved glycaemic control in patients with comorbid diabetes mellitus, with SSRIs recommended as the preferred choice.
Why the study?
Do antidepressants improve depressive symptoms and glycaemic control in patients with depression and comorbid diabetes mellitus?
Systematic Review
Do antidepressants improve depressive symptoms and glycaemic control in patients with depression and comorbid diabetes mellitus?
SSRIs are recommended for treating depression in patients with diabetes, as antidepressant therapy improves both depressive symptoms and glycaemic control, though hypoglycemia risk requires monitoring.
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SSRIs may be preferred for depression with DM; limited evidence leaves optimal selection open for larger RCTs.
Roopan et al. (2016) conducted a systematic review in Depression and comorbid diabetes mellitus. Antidepressants was evaluated on Depressive symptoms and glycaemic control. Antidepressant treatment reduced depressive symptoms and improved glycaemic control in patients with comorbid diabetes mellitus, with SSRIs recommended as the preferred choice.
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