Key result
A combination of risk factors including hypertension, dyslipidemia, BMI, and physical inactivity was significantly associated with NAFLD in newly diagnosed T2DM patients (P=0.001).
Why the study?
Prevalence of obesity and T2DM, both related to NAFLD, is increasing among Asian people, but data on NAFLD prevalence and its risk factors in T2DM in Southern Pakistan were needed.
What is the prevalence of NAFLD and its associated risk factors in recently diagnosed T2DM patients in Pakistan?
Cross-Sectional
No
What is the prevalence of NAFLD and its associated risk factors in recently diagnosed T2DM patients in Pakistan?
p-value: p== 0.001
There is a high incidence of NAFLD associated with lifestyle-related factors in newly diagnosed T2DM patients in Pakistan, highlighting the need for early screening.
High NAFLD prevalence in new T2DM supports screening consideration in South Asians; leaves open need for prospective validation.
AIM: Prevalence of obesity and type 2 diabetes mellitus (T2DM), both of which represent are related to nonalcoholic fatty liver disease (NAFLD), is an increasing trend among Asian people. The study aimed to assess the prevalence of NAFLD in T2DM with their risk factors in the Southern part of Pakistan. MATERIALS AND METHODS: A cross-sectional study was accomplished during 2008-2013 at The Aga Khan University Hospital, Karachi, Pakistan. Adult patients diagnosed with T2DM during last 6 months were enrolled in this study. NAFLD was identified using ultrasound of the liver. Clinical and biochemical relevant measurements were accomplished. RESULTS: = 0.001) was found for the combination of hypertension, dyslipidemia, body mass index (BMI), waist circumference, lack of physical inactivity, triglycerides, lower HDL, LDL, HbA1c, and ALT (multiplicative analysis). CONCLUSION: High incidence of NAFLD with the association of different lifestyle-related factors has been analyzed. It unmasks the need for screening for NAFLD in newly diagnosed DM patients in Pakistan with the assessment of parameters of risk factors. HOW TO CITE THIS ARTICLE: Nonalcoholic fatty Liver Diseases Among Recently Diagnosed Patients With Diabetes Mellitus and Risk Factors. Euroasian J Hepatogastroenterol 2019;9(1):9-13.
No takes yet. Share an insight, caveat, or question.
Hamid et al. (2019) conducted a cross-sectional in Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease. Clinical and biochemical risk factors (e.g., hypertension, dyslipidemia, BMI, physical inactivity) was evaluated on Prevalence of NAFLD and its association with risk factors (p== 0.001). A combination of risk factors including hypertension, dyslipidemia, BMI, and physical inactivity was significantly associated with NAFLD in newly diagnosed T2DM patients (P=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: