Key result
An ECG morphology with a QS in aVR and monophasic R in aVL predicted para-Hisian premature ventricular complexes with 92.8% sensitivity and 93.9% specificity.
Why the study?
Catheter ablation of para-Hisian premature ventricular complexes carries a high risk of heart block, prompting the search for electrocardiographic predictors.
Can specific ECG characteristics predict the para-Hisian location of premature ventricular complexes in patients undergoing catheter ablation?
Observational (n=47)
Can specific ECG characteristics predict the para-Hisian location of premature ventricular complexes in patients undergoing catheter ablation?
A PVC morphology with a QS in aVR, monophasic R in aVL, and QRS width <143 msec reliably predicts a para-Hisian location, which is critical given the high risk of heart block during ablation in this region.
Background Catheter ablation of para‐Hisian ( PH ) premature ventricular complexes ( PVC s) has a high risk of heart block. This study aimed to find the electrocardiographic ( ECG ) predictors of PH ‐ PVC s. Methods We enrolled 47 patients who underwent an electrophysiologic study for catheter ablation of PVC s and analyzed the ECG characteristics, retrospectively. Results The PVC locations were the PH in 14, right ventricular ( RV ) outflow tract ( OT ) in 11, left ventricular ( LV ) OT in 16, LV septum in 5, and LV summit in 1. The QRS width of the PH ‐ PVC s was significantly narrower than that of the rest of PVC s (140.9 ± 17.1 ms vs. 158.9 ± 19.4 ms, P = 0.004). Precordial transition of the PH ‐ PVC s related to sinus rhythm was not helpful in predicting the location. Lead I had monophasic R waves in 100% and lead aVR QS waves in 100%. In aVL , 13 of 14 patients had monophasic R waves, and 1 had biphasic ( rS ) waves with an initial positive polarity. Among the study cohort, 15 patients had a QS in aVR and R in aVL , including 13 PH ‐ PVC s and 2 PVC s coming from the RVOT septum and LVOT septum, respectively. The QS in aVR and monophasic R in aVL had a sensitivity of 92.8%, specificity of 93.9%, positive predictive value of 86.7%, and negative predictive value of 96.9% for localizing PH‐PVCs. Conclusions A PVC morphology with a QS in aVR and monophasic R in aVL and QRS width <143 msec, could be used as a reliable parameter for predicting the PH location.
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Hwang et al. (2018) conducted an observational in Premature ventricular complexes (n=47). ECG morphology (QS in aVR and monophasic R in aVL) vs. Other ECG morphologies was evaluated on Localization of para-Hisian PVCs (Sensitivity 92.8%, Specificity 93.9%). An ECG morphology with a QS in aVR and monophasic R in aVL predicted para-Hisian premature ventricular complexes with 92.8% sensitivity and 93.9% specificity.
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