Key result
Meta-vinculin is localized in the same cellular adhesive structures as vinculin, including membrane-associated microfilament-bound plaques of smooth muscle and intercalated discs of cardiac muscle.
Population
Human uterus smooth muscle, human aorta smooth muscle cells, and cardiac muscle
Design
Preclinical
Authors
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Suggests coordinated adhesion roles in muscle; leaves open functional or clinical relevance in cardiac disease.
Meta-vinculin is identified as a structural component of microfilament-membrane attachment sites in smooth and cardiac muscles.
Belkin et al. (1988) studied this question. Immunolocalization of meta-vinculin was evaluated on Localization of meta-vinculin in smooth and cardiac muscles. Meta-vinculin is localized in the same cellular adhesive structures as vinculin, including membrane-associated microfilament-bound plaques of smooth muscle and intercalated discs of cardiac muscle.
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