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This research aims to explore a new palladium-catalyzed approach for synthesizing 1,5-dienes and 1,5-enynes.

Palladium-catalyzed cross-coupling reaction of homoallylic or homopropargylic organozincs with alkenyl halides as a new selective route to 1,5-dienes and 1,5-enynes

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Randomized trial demonstrates a new selective route to 1,5-dienes and 1,5-enynes using organozincs.

This research aims to explore a new palladium-catalyzed approach for synthesizing 1,5-dienes and 1,5-enynes.
Utilized palladium-catalyzed cross-coupling reactions.
Employed homoallylic and homopropargylic organozincs with alkenyl halides.
Investigated the selectivity of the reaction towards desired products.
Successfully synthesized various 1,5-dienes and 1,5-enynes.
Indicated high selectivity for the desired products amid competing reactions.
Demonstrated potential implications for future organic synthesis methodologies.

Negishi et al. (1980) studied this question.

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