What question did this study set out to answer?

The study aims to evaluate lymphatic vasculature in various cardiac pathological conditions, including ischaemia and atherosclerosis.

Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions

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Randomized trial shows increased lymphatics in cardiac conditions, suggesting therapeutic implications.

The study aims to evaluate lymphatic vasculature in various cardiac pathological conditions, including ischaemia and atherosclerosis.
Used immunohistochemistry with CD 31, podoplanin, and LYVE-1 to assess lymphatic vasculature.
Analyzed 36 autopsy hearts from children and adults, including valve biopsies from eight adults.
Identified lymphatic density in multiple cardiac conditions.
Infective endocarditis valves showed nearly 100% lymphatics in certain areas.
Increased lymphatics in degenerative calcified stenosis and atherosclerotic lesions rich in calcium/cholesterol.
Epicardium of ischaemic hearts had the highest myocardial lymphatics in both acute and chronic phases.

Kholová et al. (2010) studied this question.

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