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The study aims to assess ridge alteration and regeneration in buccal-bone-deficient extraction sockets following grafting with rhBMP-2.

Ridge regeneration of damaged extraction sockets using rhBMP‐2: an experimental study in canine

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Experimental study evaluates ridge regeneration in canine extraction sockets with rhBMP-2 or membrane cover, highlighting potential treatments.

The study aims to assess ridge alteration and regeneration in buccal-bone-deficient extraction sockets following grafting with rhBMP-2.
Conducted in five beagle dogs with surgical removal of buccal bone from extracted premolar sockets.
Graft protocols included sham surgery, deproteinized bovine bone mineral, DBBM/rhBMP-2, and DBBM covered with a collagen membrane.
Radiographic and histological analyses were performed after 8 weeks.
Grafted sites showed reduced dimensional changes compared to non-grafted controls.
Minimal regeneration was observed in DBBM-only sites, while DBBM/rhBMP-2 and DBBM/Membrane sites exhibited significant new bone formation.
Socket grafting with rhBMP-2 or membrane covering can effectively preserve buccolingual dimension.

Lee et al. (2015) studied this question.

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Experimental study evaluates ridge regeneration in canine extraction sockets with rhBMP-2 or membrane cover, highlighting potential treatments.