Key result
Primary Ewing sarcoma of the kidney is a rare malignancy presenting with nonspecific symptoms, requiring multimodal treatment, and carrying a poor prognosis in metastatic disease.
Primary Ewing sarcoma of the kidney is a rare urologic malignancy requiring multimodal treatment, though prognosis for metastatic disease remains poor.
Ewing sarcoma and primitive peripheral neuroectodermal tumor (PNET) are high-grade malignant tumors typically found in children and adolescents. These tumors belong to the family of small round cell tumors and are of neuroectodermal origin. Primary Ewing sarcoma of the kidney is rare and because of that is an infrequent differential diagnosis in urologic malignancies. Renal PNET mostly presents with nonspecific symptoms such as hematuria and abdominal pain. The imaging findings are uncharacteristic. The diagnosis is based on the histology, immunohistochemistry, and molecular pathologic findings. Once PNET has been diagnosed, multimodal treatment is indicated. Despite all treatment options, the prognosis of those with metastatic disease is poor.
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Almeida et al. (2014) conducted a review in Ewing sarcoma of the kidney. Primary Ewing sarcoma of the kidney is a rare malignancy presenting with nonspecific symptoms, requiring multimodal treatment, and carrying a poor prognosis in metastatic disease.
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