Key result
Transcatheter edge-to-edge repair has evolved as a revolutionary treatment for severe mitral regurgitation, with expanding indications for challenging anatomies and ongoing improvements in device design.
Why the study?
Despite surgical mitral valve interventions, up to half of severe MR patients do not receive surgery, motivating transcatheter edge-to-edge repair devices whose evolution and future directions require discussion.
This review discusses the evolution, current case selection, and future advances of transcatheter edge-to-edge repair for mitral and tricuspid regurgitation.
Supports expanding transcatheter edge-to-edge repair to complex anatomies; leaves open the need.
Severe mitral regurgitation (MR) is associated with heart failure and impaired survival with an annual mortality risk in excess of 5% per year for unoperated patients. Despite availability of surgical mitral valve interventions, as many as half of all patients with severe MR do not receive interventions. Transcatheter edge-to-edge repair with MitraClip has been a revolutionary therapy for MR, with over 100,000 treated patients worldwide. The usage has also expanded to different challenging anatomies as well as tricuspid regurgitation. Additionally, other transcatheter edge-to-edge repair devices are being studied. The evolution of these devices as well as what to expect in the future will be discussed here.
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Sorajja et al. (2021) conducted a review in Mitral regurgitation. Transcatheter edge-to-edge repair was evaluated. Transcatheter edge-to-edge repair has evolved as a revolutionary treatment for severe mitral regurgitation, with expanding indications for challenging anatomies and ongoing improvements in device design.
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