Key result
Cardiac MRI confirmed the diagnosis of cytarabine-induced acute pericarditis by revealing pericardial edema and late gadolinium enhancement after an inconclusive echocardiogram.
Why the study?
Pericarditis is a rare but debilitating complication of cytarabine therapy, and cardiac MRI offers superior accuracy over echocardiography in establishing the diagnosis.
Does cardiac MRI confirm the diagnosis of cytarabine-induced pericarditis when echocardiography is inconclusive?
Case Report (n=1)
Does cardiac MRI confirm the diagnosis of cytarabine-induced pericarditis when echocardiography is inconclusive?
Cardiac MRI is an effective imaging modality to confirm cytarabine-induced pericarditis when echocardiography is inconclusive.
Answers are grounded in this paper and cite their sources.
Cardiac MRI may confirm cytarabine-induced pericarditis in AML; hypothesis-generating for routine use.
Pericarditis is a rare but debilitating complication of cytarabine therapy. While echocardiography can aid with the diagnosis, cardiac MRI has superior accuracy in establishing the diagnosis. In this case, we describe a 65-year-old patient receiving cytarabine as part of induction chemotherapy for acute myeloid leukemia who developed acute pericarditis. Her cardiac MRI revealed pericardial edema on T2-weighted STIR imaging and pericardial late gadolinium enhancement which confirmed the diagnosis.
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Dong et al. (2021) conducted a case report in Acute myeloid leukemia with acute pericarditis (n=1). Cardiac MRI vs. Echocardiography was evaluated on Confirmation of pericarditis diagnosis. Cardiac MRI confirmed the diagnosis of cytarabine-induced acute pericarditis by revealing pericardial edema and late gadolinium enhancement after an inconclusive echocardiogram.
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