Key result
Cardiac MRI confirmed cytarabine-induced acute pericarditis in a 65-year-old woman by revealing pericardial edema on T2-weighted STIR imaging and pericardial late gadolinium enhancement.
Why the study?
Pericarditis is a rare but debilitating complication of cytarabine therapy, and cardiac MRI offers superior accuracy over echocardiography in establishing the diagnosis.
Case Report (n=1)
Cardiac MRI can accurately confirm the diagnosis of cytarabine-induced acute pericarditis by detecting pericardial edema and late gadolinium enhancement.
Alerts clinicians to consider cardiac MRI for suspected cytarabine pericarditis; leaves open need for prospective validation versus echocardiography.
Pericarditis is a rare but debilitating complication of cytarabine therapy. While echocardiography can aid with the diagnosis, cardiac MRI has superior accuracy in establishing the diagnosis. In this case, we describe a 65-year-old patient receiving cytarabine as part of induction chemotherapy for acute myeloid leukemia who developed acute pericarditis. Her cardiac MRI revealed pericardial edema on T2-weighted STIR imaging and pericardial late gadolinium enhancement which confirmed the diagnosis.
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Dong et al. (2021) conducted a case report in Cytarabine-induced pericarditis (n=1). Cytarabine was evaluated on Diagnosis of acute pericarditis. Cardiac MRI confirmed cytarabine-induced acute pericarditis in a 65-year-old woman by revealing pericardial edema on T2-weighted STIR imaging and pericardial late gadolinium enhancement.
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