Meta-analysis for the value of colchicine for the therapy of pericarditis and of postpericardiotomy syndrome

Fig. 1. Flow chart for the selection of studies. The flow diagram represents the number of studies reviewed and included in the analysis

Fig. 2. Funnel plot of the studies included in the meta-analysis. The individual studies are represented by blue dots and they distributed around the mean value, which is represented by the dotted vertical line. The risk ratio is depicted on the X axis opposite to the standard error on the Y axis

Fig. 3. Forest plot graph for the meta-analysis on PE prevention or recurrent PE in pericarditis or post-operative patients by colchicine. The mean relative risk (RR) is represented with the blue diamond and the dotted vertical line. The red squares show the RR for the individual studies, the horizontal lines show the corresponding 95% confidence intervals. Experimental: study group treated with colchicine; Control: control group. Events: sum of events, Total: number of patients of the corresponding group, RR: relative risk

Fig. 4. Forest plot graph for the meta-analysis of pericarditis recurrence under colchicine. Upper graph: all patients with pericarditis, middle graph: patients with acute pericarditis, bottom graph: patients with recurrent pericarditis. The mean relative risk (RR) is represented with the blue diamond and the dotted vertical line. The red squares show the RR for the individual studies, the horizontal lines show the corresponding 95% confidence intervals. Experimental: study group treated with colchicine; Control: control group. Events: sum of events, Total: number of patients of the corresponding group, RR: relative risk

Fig. 5. Forest plot graph for the meta-analysis of the incidence of Post-Pericardiotomy Syndrome (PPS). The mean relative risk (RR) is represented with the blue diamond and the dotted vertical line. The red squares show the RR for the individual studies, the horizontal lines show the corresponding 95% confidence intervals. Experimental: study group treated with colchicine; Control: control group. Events: sum of events, Total: number of patients of the corresponding group, RR: relative risk

Fig. 6. Forest plot graph for the meta-analysis of the rehospitalization rate. Upper graph: all patients, middle graph: pericarditis, bottom graph: post-pericardiotomy syndrome. The mean relative risk (RR) is represented with the blue diamond and the dotted vertical line. The red squares show the RR for the individual studies, the horizontal lines show the corresponding 95% confidence intervals. Experimental: study group treated with colchicine; Control: control group. Events: sum of events, Total: number of patients of the corresponding group, RR: relative risk

Fig. 7. Forest plot graph for the meta-analysis of the symptom persistence after 72 h. The mean relative risk (RR) is represented with the blue diamond and the dotted vertical line. The red squares show the RR for the individual studies, the horizontal lines show the corresponding 95% confidence intervals. Experimental: study group treated with colchicine; Control: control group. Events: sum of events, Total: number of patients of the corresponding group, RR: relative risk

Fig. 8. Forest plot graph for the meta-analysis of the adverse events. The mean relative risk (RR) is represented with the blue diamond and the dotted vertical line. The red squares show the RR for the individual studies, the horizontal lines show the corresponding 95% confidence intervals. Experimental: study group treated with colchicine; Control: control group. Events: sum of events, Total: number of patients of the corresponding group, RR: relative risk