Key result
Comprehensive CMR with parametric mapping detects subclinical myocardial inflammation and fibrosis in autoimmune rheumatic diseases.
Why the study?
Cardiovascular disease is the leading cause of morbidity and mortality in autoimmune rheumatic diseases, and advances in comprehensive cardiac magnetic resonance techniques may improve patient diagnosis, risk stratification, and management.
Does comprehensive stress cardiac MRI improve the early diagnosis and risk stratification of cardiovascular involvement in patients with autoimmune rheumatic disease?
Does comprehensive stress cardiac MRI improve the early diagnosis and risk stratification of cardiovascular involvement in patients with autoimmune rheumatic disease?
Comprehensive stress cardiac MRI is a valuable non-invasive tool for identifying underdiagnosed myocardial inflammation and coronary microvascular dysfunction in patients with autoimmune rheumatic diseases.
Answers are grounded in this paper and cite their sources.
May support subclinical cardiac detection in autoimmune rheumatic diseases; leaves open prospective validation for risk stratification.
Cardiovascular disease is the leading cause of morbidity and mortality in patients with autoimmune rheumatic diseases. Much of this may be attributed to systemic inflammation resulting in coronary atherosclerosis and myocarditis. Cardiac magnetic resonance imaging is the gold standard for the evaluation of cardiac structure and function, including tissue characterization, which allows for detection of myocardial edema, inflammation, and fibrosis. Advances in parametric mapping and coronary flow reserve measurement techniques have the potential to change the diagnosis, risk stratification, and management of patients with autoimmune rheumatic diseases. We provide an overview of the current evidence and suggest potential future roles for the use of comprehensive cardiac magnetic resonance in patients with autoimmune rheumatic diseases in the field of cardio-rheumatology.
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Varghese et al. (2024) conducted a review in Autoimmune rheumatic diseases (AIRD). Comprehensive stress cardiac magnetic resonance imaging (CMR) was evaluated. Comprehensive cardiac magnetic resonance imaging with parametric mapping can detect subclinical myocardial inflammation, fibrosis, and microvascular dysfunction in autoimmune rheumatic diseases.
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