Key points are not available for this paper at this time.
A half-century has elapsed since the first transplantation, and this procedure is now accepted as the treatment of choice for end-stage organ failure. This article reviews the many developments since that historic moment. Although tremendous progress has contributed to the success of this form of therapy, several challenges remain if transplantation is to be widely available with minimal risks and optimal outcomes.
Sayegh et al. (Wed,) studied this question.