Key result
Wide ECG QRS-T angle correlates with RV overload and aids early pulmonary hypertension screening.
Why the study?
ECG is a cheap and noninvasive test whose clinical significance in the diagnosis of pulmonary hypertension warrants further study.
Does the QRS-T angle derived from an ECG predict pulmonary arterial hypertension?
Does the QRS-T angle derived from an ECG predict pulmonary arterial hypertension?
The QRS-T angle derived from a standard 12-lead ECG represents a widely available, low-cost tool that could improve early screening for pulmonary hypertension.
Spatial QRS-T angle is a vector projection of ventricular gradient, reflecting the heterogeneity of ventricular repolarization. The QRS vector is projected into three dimensional (3D) space to obtain the frontal QRSf vector and Tf vector. The frontal QRS-T Angle can be obtained by simple calculation. In several studies of diseases that cause pulmonary hypertension, there has been evidence that changes in the QRS-T Angle can predict disease. Electrocardiogram (ECG) is a cheap and noninvasive test, and its clinical significance in the diagnosis of pulmonary hypertension should be further studied.
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Li et al. (2023) conducted a review in Pulmonary arterial hypertension. Wide QRS-T angle vs. Normal QRS-T angle was evaluated. Wide QRS-T angles on standard electrocardiograms correlate with right ventricular overload and serve as promising noninvasive markers for the early screening and prediction of pulmonary hypertension.
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