Key result
Office, 24-hour, and daytime pulse pressure were independent predictors of cardiovascular events over 137 months of follow-up in the general population, with nighttime pulse pressure predicting risk in men.
Why the study?
Does pulse pressure predict cardiovascular events in the general population?
Cohort (n=2,045)
Does pulse pressure predict cardiovascular events in the general population?
Pulse pressure, particularly daytime and 24-hour measurements, is an independent predictor of cardiovascular events in the general population, with nighttime PP showing additional predictive value specifically in men.
Pulse pressure may predict CV events in the general population and by sex; leaves open its incremental value for risk stratification.
The aim of the present study is to investigate the predictive value of pulse pressure (PP) on cardiovascular events in the general population and in both sexes, separately. The study involved 2045 participants from the PAMELA study who underwent 24-hour ambulatory blood pressure (BP) monitoring. The participants were followed from the initial medical visit for a time interval of 137 ± 23 months. It was found that office, home, and 24-hour blood pressures were significantly higher in the individuals who experienced cardiovascular (CV) events. Office, 24-hour, and daytime PP were independent predictors of CV events after adjustment for main demographic and clinical parameters in the whole study population. Nighttime PP was an additional independent predictor in men. In conclusion, PP represents an important predictor of cardiovascular events in the general population, particularly among men. Daytime and 24-hour PP have greater predictive importance than nighttime PP in the general population.
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Tadić et al. (2018) conducted a cohort in General population (n=2,045). Pulse pressure was evaluated on Cardiovascular events. Office, 24-hour, and daytime pulse pressure were independent predictors of cardiovascular events over 137 months of follow-up in the general population, with nighttime pulse pressure predicting risk in men.
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