November 3, 2021Open Access
Habitual physical activity and central artery stiffening in older adults: The Atherosclerosis Risk in Communities study
Key result
High physical activity was associated with lower central arterial stiffness (adjusted mean difference in cfPWV 0.38 m/s) compared with no physical activity in older adults.
Why the study?
It is not clear whether the reduced arterial stiffening associated with habitual physical activity is observed in community-dwelling older adults.
Does moderate or high physical activity reduce central arterial stiffness and pressure pulsatility in community-dwelling older adults?
Population
3893 older adults
Comparison
Moderate or high physical activity vs no physical activity
Design
Prospective cohort study
Authors
Discussion
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Member takes
Implication
Physical activity may link to lower stiffness in older adults; hypothesis-generating and should not yet change practice.
Study Design
Type
Cohort (n=3,893)
Structured PICO
Does moderate or high physical activity reduce central arterial stiffness and pressure pulsatility in community-dwelling older adults?
P
Population
3,893 community-dwelling older adults evaluated for the association between habitual physical activity and central arterial stiffness.
E
Exposure
Moderate or high physical activity (including persistent physical activity from mid-life to late-life)
C
Comparator
No physical activity
O
Outcome
Central arterial stiffness (measured via carotid-femoral pulse wave velocity or cfPWV) and pressure pulsatility (measured via central pulse pressure or cPP)surrogate
Main Result
Mean Difference: 0.38
Habitual and late-life physical activity are associated with reduced central arterial stiffness and pressure pulsatility in community-dwelling older adults.
Cite This Study
Matsushita et al. (2021) conducted a cohort in Community-dwelling older adults (n=3,893). Habitual physical activity vs. No physical activity was evaluated on Central arterial stiffness (cfPWV) and pressure pulsatility (cPP) (MD 0.38). High physical activity was associated with lower central arterial stiffness (adjusted mean difference in cfPWV 0.38 m/s) compared with no physical activity in older adults.