1,6-Conjugate Addition of Nucleophiles to α,β,γ,δ-Diunsaturated Systems

Herein, an overview of the most important developments and concepts related to the 1,6-conjugate addition reactions are reviewed. 1 Introduction 2 Transition-Metal-Catalyzed 1,6-Conjugate Additions 2.1 Copper-Mediated Reactions 2.2 Iron-Mediated Reactions 2.3 Rhodium- and Iridium-Mediated Reactions 3 Organocatalyzed 1,6-Conjugate Additions 4 Other Methods 5 Conclusions