Targeted isolation of FabG inhibitors from Koelreuteria bipinnata leaves: Mechanistic insights, synergistic antibacterial effects, and cytoprotection.

Key Points

• The study aims to isolate FabG inhibitors from K. bipinnata leaves and evaluate their cytoprotective and antibacterial properties.
• Isolated extracts from K. bipinnata leaves targeting FabG inhibitors.
• Assessed the impact on cell viability under oxidative stress conditions.
• Evaluated synergistic antibacterial effects of the extracts.
• Cell viability increased from 71.25% to 92.56% after treatment with K. bipinnata extracts under oxidative stress.