Key result
Ileal angiosarcoma resection precedes suspected peritoneal progression at ~6 months due to chemotherapy intolerance.
Why the study?
Primary angiosarcoma of the ileum is extremely uncommon with few reported cases, posing diagnostic challenges due to nonspecific symptoms.
Case Report (n=1)
Primary ileal angiosarcoma is an extremely rare and aggressive tumor that can present with nonspecific symptoms like subocclusive syndrome and mimic Crohn's disease on imaging.
Rare ileal angiosarcoma may mimic Crohn’s on MRI; leaves open need for histopathology in atypical stenoses.
Introduction: Angiosarcomas are rare malignant vascular tumors. Primary angiosarcoma of the ileum is extremely uncommon, with few cases reported in the literature. Case Report: We report the case of a 54-year-old woman who presented with abdominal pain and constipation. Endoscopic evaluation did not reveal a mass in the distal ileum; however, MRI identified a distal ileal stenosis, raising suspicion for Crohn’s disease. Surgical resection was performed, and histopathological analysis confirmed the diagnosis of primary ileal angiosarcoma. Postoperative chemotherapy was attempted but not tolerated, and the patient subsequently developed suspected peritoneal progression approximately six months after surgery. Discussion: Due to its rarity and nonspecific symptoms, ileal angiosarcoma is often diagnosed late. Imaging may suggest a vascular tumor, but definitive diagnosis requires histopathological and immunohistochemical analysis. Prognosis is generally poor, with high metastatic potential. Conclusions: This case highlights the diagnostic challenges of ileal angiosarcoma, a very rare type of tumor of the small bowel.
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Milaciu et al. (2026) conducted a case report in Primary ileal angiosarcoma (n=1). Surgical resection and postoperative chemotherapy was evaluated on Clinical outcome. Surgical resection of a stenosing ileal angiosarcoma was followed by suspected peritoneal progression approximately six months after surgery due to intolerance of postoperative chemotherapy.
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