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Analyzes neurofilament light chain's role in diagnosis and prognosis of traumatic brain injury, indicating its clinical significance.
Neurofilament Light Chain (NfL), as a sensitive biomarker of neuronal axonal injury, holds significant value in the diagnosis, prognosis assessment, and treatment of Traumatic Brain Injury (TBI). This study integrates data from bioinformatics, basic experiments, and clinical research to systematically analyze the multi-dimensional role of NfL in TBI. NfL has important biological and clinical significance in TBI. As a sensitive biomarker of neural injury, it provides new research directions for the early diagnosis, prognosis assessment, and treatment of TBI.
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Zhao et al. (2026) studied this question.
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