Key result
Pathological Q waves in children with acute myocarditis were associated with severe complications, with all deaths or discharges with LVEF < 30% occurring in the Q wave group (P=0.069).
Why the study?
Pathological Q waves are linked to permanent damage and myocardial death in several cardiac diseases, but their significance in children with acute myocarditis remains underinvestigated.
Does the presence of pathological Q waves on ECG predict poorer hospital outcomes in children with acute myocarditis?
Observational (n=59)
No
Does the presence of pathological Q waves on ECG predict poorer hospital outcomes in children with acute myocarditis?
p-value: p== 0.069
The presence of pathological Q waves on ECG in pediatric acute myocarditis is a readily available prognostic marker associated with severe complications, including death or severe left ventricular dysfunction.
Pathological Q waves may flag higher-risk pediatric myocarditis; leaves open utility for risk stratification pending prospective validation.
BACKGROUND: Myocarditis is an uncommon disease in children with potentially fatal consequences. An electrocardiogram (ECG) change seen in myocarditis is pathological Q wave. Pathological Q wave is linked to permanent damage and myocardial death in several cardiac diseases. We investigated the significance of pathological Q waves in children with acute myocarditis (AM). METHODS: This retrospective observational study analysed the data of 59 children with AM admitted to our hospital between January 2016 and July 2021. They were divided into Q wave and non-Q wave myocarditis groups. Patients' laboratory data, echocardiography, treatment and hospital outcome were analysed. RESULTS: = 0.069). All the patients who died or discharged with an LVEF < 30% belonged to the Q wave group. CONCLUSION: Q wave in AM warrants close monitoring and intensive treatment as it accompanies more severe complications and poorer outcomes. This readily available ECG finding can be a clue to prognoses of AM patients. Further research with larger populations is needed to better understand Q wave prognostic accuracy and its potential role in guiding more expensive treatments.
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Mohammadi et al. (2022) conducted an observational in Acute myocarditis (n=59). Pathological Q wave vs. Non-Q wave was evaluated on Death or discharge with LVEF < 30% (p== 0.069). Pathological Q waves in children with acute myocarditis were associated with severe complications, with all deaths or discharges with LVEF < 30% occurring in the Q wave group (P=0.069).
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