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February 3, 2025Experimental and Clinical GastroenterologyOpen Access

Effects of therapeutic factors on brown adipose tissue in order to correct obesity

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Key result

Activating brown adipose tissue through physical activity, medications, and supplements shows promise against obesity.

Why the study?

White adipose tissue drives obesity and metabolic disease, whereas activating brown adipose tissue or stimulating browning via therapeutic factors represents a promising strategy to treat overweight and obesity.

Design

Review

Authors

DKD. P. KurmaevSamara State Medical UniversityСБС. В. БулгаковаSechenov UniversityETE. V. TrenevaMinistry of Health of the Russian Federation

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Implication

May inform obesity therapies targeting adipose tissue; leaves open validation in randomized trials.

PICO

P
Population
Obesity
I
Intervention / Comparator
Therapeutic factors (physical activity, medications, dietary supplements)

Activating brown adipose tissue and promoting the 'browning' of white fat represent promising therapeutic strategies for managing obesity and related metabolic diseases.

Cite This Study

Kurmaev et al. (2025) conducted a review in Obesity. Therapeutic factors (physical activity, medications, dietary supplements) was evaluated. Activation of brown adipose tissue and browning of white adipocytes through physical activity, medications, and dietary supplements represent promising strategies for combating overweight and obesity.

synapsesocial.com/papers/6a5f17dd3ded86b8acaf0372https://doi.org/10.31146/1682-8658-ecg-228-8-7-27
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Also Consider

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  4. 4A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function2020 · 164 citations
  5. 5Browning of Adipocytes: A Potential Therapeutic Approach to Obesity2023 · 47 citations