Key result
Patients with carotid artery disease had larger bifurcation angles (151 vs 144 degrees) and smaller external carotid artery diameters (4.6 vs 5.2 mm) compared with healthy controls.
Why the study?
What are the morphometric and hemodynamic differences in carotid artery bifurcations between patients with carotid artery disease and healthy controls?
Population
Chinese control subjects (n = 30) and patients with carotid artery disease (n = 30)
Design
Case-control
Authors
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Carotid bifurcation geometry and flow differ in atherosclerotic patients vs controls; leaves open whether these changes drive progression.
Case-Control (n=60)
What are the morphometric and hemodynamic differences in carotid artery bifurcations between patients with carotid artery disease and healthy controls?
Morphometric and hemodynamic analyses suggest that atherosclerotic plaques initiate at both the sinus and carina regions of the internal carotid artery and progress downstream.
Huang et al. (2016) conducted a case-control in Carotid artery disease (n=60). Carotid artery disease vs. Healthy control subjects was evaluated on Morphometric and hemodynamic differences (vector angles and vessel diameters). Patients with carotid artery disease had larger bifurcation angles (151 vs 144 degrees) and smaller external carotid artery diameters (4.6 vs 5.2 mm) compared with healthy controls.
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