Key result
Each syndemic condition was associated with 8% greater odds of atherosclerotic plaque (OR 1.08), 9% greater odds of systolic blood pressure, and 10% greater odds of diastolic blood pressure.
Why the study?
Research examining the association between syndemic conditions and cardiovascular risk in high-risk populations is lacking.
Does the presence of syndemic conditions increase the risk of atherosclerotic plaque and elevated blood pressure in a high-risk population?
Cross-Sectional (n=503)
Does the presence of syndemic conditions increase the risk of atherosclerotic plaque and elevated blood pressure in a high-risk population?
The accumulation of syndemic conditions is associated with a stepwise increase in the odds of subclinical atherosclerosis and elevated blood pressure in a high-risk, predominantly African-American cohort.
Answers are grounded in this paper and cite their sources.
Syndemic conditions may elevate CV risk; hypothesis-generating and should not yet change practice.
The syndemic conditions of low education, childhood maltreatment, depression, HIV, alcohol and cocaine use, and obesity have been established as independent risk factors for cardiovascular risk, but research examining the association between syndemic conditions and cardiovascular risk in high-risk populations is lacking. A total of N = 503 participants underwent an ultrasound of the carotid artery to assess for atherosclerotic plaque. Participants, HIV-infected (n = 202) and HIV-uninfected (n = 301) with and without a history of cocaine use, were a mean age of 36.13 years (SD = 9.51); 50% were male, and 62% were African-American. Each syndemic condition was associated with 8% greater odds of atherosclerotic plaque (OR = 1.08), 9% greater odds of systolic blood pressure (OR = 1.09), and 10% greater odds of diastolic blood pressure (OR = 1.10). Multilevel research, interventions, and public policy initiatives are needed to activate stakeholders at each level to maximize their impact at a community level among populations with high rates of syndemic conditions.
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Rodriguez et al. (2020) conducted a cross-sectional in Cardiovascular disease risk (n=503). Syndemic conditions vs. Fewer syndemic conditions was evaluated on Atherosclerotic plaque (OR 1.08). Each syndemic condition was associated with 8% greater odds of atherosclerotic plaque (OR 1.08), 9% greater odds of systolic blood pressure, and 10% greater odds of diastolic blood pressure.
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