Key result
High psychosocial risk was associated with increased prevalence of carotid artery focal plaque among women living with HIV (23% vs 11%; aOR 2.12, 95% CI 1.11-4.05), but not among HIV-negative women.
Why the study?
To identify reasons for increased atherosclerotic risk among women living with HIV by evaluating associations between psychosocial risk factors and subclinical atherosclerosis.
Are high psychosocial risk factors associated with increased subclinical carotid atherosclerosis in women living with HIV?
Population
700 women living with HIV and HIV-negative women
Comparison
High vs low psychosocial risk classes and persistent vs non-persistent depressive symptoms
Design
Cohort study
Authors
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Psychosocial screening may identify higher-risk WLWH; leaves open whether interventions alter plaque progression.
Cohort (n=700)
Are high psychosocial risk factors associated with increased subclinical carotid atherosclerosis in women living with HIV?
Odds Ratio: 2.12 (95% CI 1.11–4.05)
Absolute Event Rate: 23% vs 11%
Psychosocial factors such as depression and stress are independent risk factors for subclinical carotid atherosclerosis specifically among women living with HIV.
Levy et al. (2020) conducted a cohort in HIV (n=700). High psychosocial risk vs. Low psychosocial risk was evaluated on Prevalent carotid artery focal plaque at final measurement among women living with HIV (aOR 2.12, 95% CI 1.11-4.05). High psychosocial risk was associated with increased prevalence of carotid artery focal plaque among women living with HIV (23% vs 11%; aOR 2.12, 95% CI 1.11-4.05), but not among HIV-negative women.
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