Key result
Patient and physiological factors including age ≥46 years, tuberculosis, base excess <-6.8 mmol/L, and serum urea >7.0 mmol/L were significantly associated with mortality (all p<0.001).
Why the study?
Patients undergoing laparotomy for emergency general surgery conditions constitute a high-risk group with poor outcomes and a high prevalence of comorbidities, motivating identification of factors that place patients at increased risk of mortality.
Population
1461 patients undergoing laparotomy for emergency general surgery conditions at Greys Hospital
Design
Retrospective analysis using decision tree discrimination
Authors
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Identified predictors may aid preoperative risk stratification in EGS laparotomy; hypothesis-generating pending prospective validation.
Cohort (n=1,461)
No
p-value: p=<0.001
Smith et al. (2021) conducted a cohort in Emergency general surgery conditions requiring laparotomy (n=1,461). Patient and physiological risk factors vs. Absence of risk factors was evaluated on Mortality (p=<0.001). Patient and physiological factors including age ≥46 years, tuberculosis, base excess <-6.8 mmol/L, and serum urea >7.0 mmol/L were significantly associated with mortality (all p<0.001).
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