Key result
Heart disease, particularly heart failure, is an important risk factor for cognitive decline through mechanisms involving hypoperfusion, immune response, and oxidative stress.
Why the study?
The effect of heart disease on brain function, defined as the heart-brain axis, is less studied despite cognitive dysfunction being a frequently reported manifestation.
Design
Review
Authors
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No immediate practice change; review extends heart-brain observations but leaves mechanisms open for prospective trials.
Cognitive dysfunction is a frequent manifestation after heart disease, particularly heart failure, driven by hypoperfusion, immune response, and oxidative stress.
Xu et al. (2021) conducted a review in Heart disease and cognitive dysfunction. Heart disease was evaluated. Heart disease, particularly heart failure, is an important risk factor for cognitive decline through mechanisms involving hypoperfusion, immune response, and oxidative stress.
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