Key result
Sevoflurane preserved myocardial function better than propofol during MIDCAB surgery, as myocardial performance index worsened to 0.49 with propofol but remained unchanged with sevoflurane.
Why the study?
Does sevoflurane preserve myocardial function compared to propofol in patients undergoing minimally invasive direct coronary artery bypass surgery?
Population
52 patients scheduled for minimally invasive direct coronary artery bypass grafting without cardiopulmonary…
Comparison
Sevoflurane vs Propofol
Design
RCT, randomly assigned
Follow-up
up to 72 h
Authors
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May support preferring sevoflurane over propofol for myocardial preservation in MIDCAB; extends RCT evidence on volatiles during brief ischemia.
RCT (n=52)
Does sevoflurane preserve myocardial function compared to propofol in patients undergoing minimally invasive direct coronary artery bypass surgery?
Sevoflurane preserves myocardial function better than propofol during the brief period of ischemia in patients undergoing MIDCAB surgery.
Bein et al. (2005) conducted an RCT in Minimally invasive direct coronary artery bypass grafting (MIDCAB) (n=52). Sevoflurane vs. Propofol was evaluated on Left ventricular performance (myocardial performance index and early to atrial filling velocity ratio). Sevoflurane preserved myocardial function better than propofol during MIDCAB surgery, as myocardial performance index worsened to 0.49 with propofol but remained unchanged with sevoflurane.
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