Key result
High animal fat diet raises total and HDL cholesterol with minimal effect on lipid ratios.
In the report by McMurry et al. in this issue of the Journal,1 native Mexicans who traditionally consume little fat were given a diet that, even by U.S. standards, was high in animal fat. Serum total cholesterol levels rose, but so did those of high-density lipoprotein (HDL) cholesterol; the ratio of total to HDL cholesterol or of low-density lipoprotein (LDL) to HDL cholesterol changed minimally. The reverse is often seen among patients who adopt a low-fat diet. In a typical example, total cholesterol may decrease markedly, from 260 to 210 mg per deciliter (6.7 to 5.4 mmol per liter), . . .
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Sacks et al. (1991) reported an editorial. High animal fat diet vs. Traditional low-fat diet was evaluated on Ratio of total to HDL cholesterol and LDL to HDL cholesterol. Administration of a high animal fat diet increased both total and HDL cholesterol levels, resulting in minimal changes to the ratio of total or LDL to HDL cholesterol.
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