Key result
Elevated platelet-to-lymphocyte ratio linked to higher in-hospital and 1-year mortality in diabetic STEMI.
Cohort (n=523)
AIM: Platelet-to-lymphocyte ratio (PLR) has emerged as a strong marker of worse outcomes. We determined the association between PLR and clinical outcomes in patients with diabetes mellitus and ST-elevation myocardial infarction. METHODS: Five hundred and twenty three patients were enrolled. Low PLR (group 1, n = 349) was defined as ≤ 124 and high PLR (group 2, n = 174) as >124. RESULTS: In-hospital and 1-year mortality was higher in group 2. Receiver operating characteristic analysis revealed moderate diagnostic value in predicting in-hospital (PLR cut-off >155) and long-term (PLR cut-off >146) death. PLR remained an independent risk factor of early and late mortality. CONCLUSION: PLR proved to have good prognostic value for in-hospital and late mortality. PLR cut-off value for predicting in-hospital mortality was higher to that predicting late mortality. PLR remained an independent risk factor early and late mortality.
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Hudzik et al. (2015) conducted a cohort in Diabetes Mellitus and ST-Elevation Myocardial Infarction (n=523). High platelet-to-lymphocyte ratio (PLR >124) vs. Low platelet-to-lymphocyte ratio (PLR ≤124) was evaluated on In-hospital and 1-year mortality. High platelet-to-lymphocyte ratio was associated with higher in-hospital (moderate diagnostic cut-off >155) and 1-year mortality (cut-off >146) in patients with diabetes mellitus and STEMI.
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