Association between Controlling Nutritional Status Score and Severity of Coronary artery stenosis in elderly patients

Background The Controlling Nutritional Status (CONUT) Score is a tool to evaluate the body nutritional state. We investigated whether the CONUT score was associated with the incidence of coronary artery disease (CAD) and the severity of coronary artery stenosis in elderly patients. Methods This study involved 3296 elderly inpatients undergone coronary angiography. A demographic and clinical profile, as well as a Gensini score, were collected. The CONUT score were evaluated by the score system. There was a correlation analysis, a multivariable logistic regression analysis, and an analysis of the receiver operating characteristic curve (ROC curve). Results Based on the quartiles of CONUT scores, 3296 elderly inpatients were divided into four groups. There were significant differences in the vessel of coronary artery stenosis among the four groups (P < 0.05). The CONUT score was significantly positively correlated with Gensini score ( r = 0.416, p < 0.001). After we divided enrolled patients into four groups by Gensini score and degree of coronary artery stenosis, the CONUT score was closely associated with the severity of coronary artery stenosis. For multivariable logistic regression, the CONUT score was risk factors of incidence of CAD and process of atherosclerosis progression after adjustment for potential confounding factors. The AUCs were 0.807 (95% CI: 0.790–0.824) for CAD, 0.717 (95% CI: 0.692–0.742) for mild stenosis, 0.842 (95% CI: 0.824–0.861) for moderate stenosis and 0.887 (95% CI: 0.867–0.908) for Severe stenosis by receiver operating characteristic analysis. Conclusions The CONUT score confers a predict factor of CAD in elderly patients, which also indicated the prognosis value in atherosclerosis progression.