Key result
Cardiomyoplasty significantly decreased left ventricular end-diastolic volume from 138 to 83 mL/m2 at 12 months (P<.01) in patients with dilated cardiomyopathy.
Why the study?
Does cardiomyoplasty improve left ventricular pressure-volume relationships in patients with dilated cardiomyopathy?
Population
6 patients with dilated cardiomyopathy
Comparison
Cardiomyoplasty (CMP) vs Baseline (before CMP)
Design
Case_series
Follow-up
6 and 12 months
Authors
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Small series in DCM suggests CMP may limit further dilatation; leaves open mechanism and clinical role pending larger data.
Observational (n=6)
Does cardiomyoplasty improve left ventricular pressure-volume relationships in patients with dilated cardiomyopathy?
Absolute Event Rate: 83% vs 138%
p-value: p=<.01
Cardiomyoplasty actively reduces left ventricular volume and improves synchronization of contraction in patients with dilated cardiomyopathy up to 1 year post-procedure.
Schreuder et al. (1997) conducted an observational in Dilated cardiomyopathy (n=6). Cardiomyoplasty vs. Baseline (before cardiomyoplasty) was evaluated on End-diastolic volume at 12 months (p=<.01). Cardiomyoplasty significantly decreased left ventricular end-diastolic volume from 138 to 83 mL/m2 at 12 months (P<.01) in patients with dilated cardiomyopathy.
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