Establishment of a Multimodal Respiratory Function Diagnostic Model and its Role in the Differential Diagnosis of Bronchial Asthma and Chronic Obstructive Pulmonary Disease with Incomplete Reversible Airflow Limitation

METHODS: that could identify them. A portion of the patients collected in the same way were used as validation samples to verify the accuracy of the model. The accuracy of the quantitative diagnostic formula, validated internally and externally using 121 patients, was 90.40% and 87.60%, respectively. CONCLUSIONS: The multimodal respiratory function diagnostic model, utilizing discriminant analysis, can distinguish asthma with incomplete reversible airflow limitation from COPD when the strongest expiratory effort is performed with an extrapolated volume ≤0.10L. CLINICAL TRIAL REGISTRATION: The study was registered on the Chinese Clinical Trial Registry (registration number: ChiCTR2400082672).