What question did this study set out to answer?

This study aims to assess long-term functional outcomes and complications following locking plate ORIF for proximal humerus fractures.

Long-term clinical outcomes and complications after Open Reduction and Internal Fixation (ORIF) with locking plate for proximal humerus fractures: a systematic review and meta-analysis

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Systematic review reports long-term functional performance and complications after ORIF in adults, suggesting careful follow-up is necessary.

This study aims to assess long-term functional outcomes and complications following locking plate ORIF for proximal humerus fractures.
A protocol-registered systematic review was conducted following PRISMA 2020 guidelines.
Ten studies with ≥ 5-year follow-up were identified from PubMed, Scopus, and Cochrane Library.
Functional outcomes and complication rates were analyzed using random-effects meta-analyses.
No significant long-term differences in CMS, DASH, or UCLA scores; OSS favored ORIF (MD 5.00; 95% CI 1.31–8.69).
Common long-term complications included AVN (5-23%), screw penetration (9-15%), stiffness, and osteoarthritis (5-16%).
Meta-analysis suggested reduced risks of complications (RR 0.06), overall reoperation (RR 0.34; 95% CI 0.13–0.87), and revision surgery (RR 0.17; 95% CI 0.07–0.45).

Conteduca et al. (2026) studied this question.

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Systematic review reports long-term functional performance and complications after ORIF in adults, suggesting careful follow-up is necessary.