Key result
In-hospital mortality for patients admitted with acute coronary syndrome was 27.4%, with significant predictors including age, time to presentation, prior hypertension, Killip class, and STEMI.
Why the study?
The study was conducted to assess the treatment outcome and associated factors for patients with acute coronary syndrome.
Cross-Sectional (n=124)
No
High ACS in-hospital mortality signals need for faster presentation and risk stratification; extends predictor validation in RCT cohorts.
Background: Acute coronary syndrome (ACS) refers to a spectrum of conditions compatible with acute myocardial ischemia and/or infarction that are usually due to an abrupt reduction in coronary blood flow. Objective: The objective of the study was to assess the treatment outcome and associated factors for ACS. Methods: A retrospective cross-sectional study was conducted from January 1, 2012 to December 31, 2014. Results: Of 124 ACS patients who were admitted during the 3 years’ period, 90 (72.6%) were diagnosed with ST segment elevation myocardial infarction (STEMI). The mean age was 56.3 ± 13.7 years. The average length of hospital stay was 9.77 ± 6.42 days. The average time from onset of ACS symptoms to presentation in the emergency department was 3.8 days (91.7 hours). In about 76 (61.3%) patients, hypertension was the leading risk factor for development of ACS, and 36.4% of ACS patients were either Killip class III or IV. Biomarkers were measured for 118 (95.2%) patients, and 79.2% of patients had ejection fraction of less than 40% and 29.2% had less than 30%. In-hospital medication use includes loading dose of aspirin (79%), anticoagulants (77.4%), beta blockers (88.1%), statins (85.5%), morphine (12.9%), and nitrates (35.5%). The in-hospital mortality was 27.4%. The predictors for in-hospital mortality were age ( P = .042), time from symptom onset to presentation ( P = .001), previous history of hypertension ( P = .025), being Killip class III and IV ( P = .001), and STEMI diagnosis ( P = .005). Conclusions: The medical management of ACS patients in Tikur Anbessa Specialized Hospital (TASH) was in line with the recommendations of international guidelines but in-hospital mortality was extremely high (27.4%).
No takes yet. Share an insight, caveat, or question.
Bogale et al. (2019) conducted a cross-sectional in Acute coronary syndrome (n=124). Risk factors for in-hospital mortality was evaluated on In-hospital mortality. In-hospital mortality for patients admitted with acute coronary syndrome was 27.4%, with significant predictors including age, time to presentation, prior hypertension, Killip class, and STEMI.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: