Key result
Severe diffuse brain injury was associated with progressive myocardial ischaemia in 3 of 7 patients, elevated catecholamines and CK-MB, and can be fatal despite optimal neurological care.
Why the study?
What are the cardiovascular effects of severe diffuse brain injury?
Population
n=7 patients with severe diffuse brain injury and no other major injury
Design
Case_series
Follow-up
72 hours
Authors
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May indicate neurogenic cardiac injury after severe brain trauma; hypothesis-generating and requires validation before clinical adoption.
Observational (n=7)
What are the cardiovascular effects of severe diffuse brain injury?
Isolated severe diffuse brain injury can lead to harmful and potentially fatal cardiac complications, including myocardial ischemia and catecholamine excess, warranting increased recognition.
McLeod et al. (1982) conducted an observational in Severe diffuse brain injury (n=7). Severe diffuse brain injury was evaluated on Cardiovascular effects including myocardial ischaemia and arrhythmias. Severe diffuse brain injury was associated with progressive myocardial ischaemia in 3 of 7 patients, elevated catecholamines and CK-MB, and can be fatal despite optimal neurological care.
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